Immunoassay Analyzers and Accessories
ProteinSimple 48-DIGOXIGENIN CARTRIDGE KIT
48-Digoxigenin Cartridge Kit Single Pack, ST01D-OT-006229
Medchemexpress LLC PLX-3618 | 2851986-76-8 | 99.7% | 601.68 | 5 MG
PLX-3618 is characterized as a molecular glue that facilitates the degradation of BRD4 with a DC50 of 12.2 nM. It achieves this by promoting the polyubiquitination and subsequent proteasomal degradation of BRD4 through the recruitment of the E3 ligase substrate receptor, DCAF11. This compound has demonstrated the ability to inhibit the proliferation of various cancer cells, induce apoptosis in acute myeloid leukemia cells, and show antitumor activity in mouse models.
- Functions as a molecular glue.
- Promotes degradation of BRD4.
- Inhibits proliferation of various cancer cells.
- Induces apoptosis in acute myeloid leukemia cells.
- Exhibits antitumor activity in mouse models.
Revvity Health Sciences Inc Cellaca PLX, Low Fluorescence Slides, 1 case with 5 boxes of 50 slides
Cellaca PLX, Low Fluorescence Slides, 1 case with 5 boxes of 50 slides
Meso Scale Discovery SPLEX HUM Eotaxin3 KitQP
The Meso Scale Discovery S-PLEX Human Eotaxin-3 Kit is a multiplex immunoassay that quantitatively measures human Eotaxin-3 in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5-logs of dynamic range and low sample volume requirements The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL tag calibrators and diluents The assay takes approximately 3 5 hours to complete and has a lower limit of detection of 19 5 pg/mL This product enables the accurate quantification of human Eotaxin-3 for research applications
Cayman Chemical DIgoxIgenIn BIsdIgItoxosID 5mg
A Na+/K+-ATPase inhibitor; an active metabolite of digoxin; inhibits the Na+/K+-ATPase isoforms α1β1 and α2β1 (Kis = 196 and 74 nM, respectively)